Psoriasis treatment options
Treatment with PsoriLess Lotion and Bio-Tronic Healing Light
Treatment:
Medical Care
* Management of the skin disease
o The simplest treatment of psoriasis is daily sun exposure, sea bathing, topical moisturizers, and relaxation.
o Topical therapy
+ Moisturizers, such as petrolatum jelly, are helpful.
+ Anthralin, coal or wood tar, corticosteroids, salicylic acid, phenolic compounds, and calcipotriene (a vitamin D analog) also may be effective.
+ Various ultraviolet light treatments are used; most commonly, PUVA therapy is used. Psoralen is a photosensitizer that is ingested prior to light exposure.
o Systemic therapy
+ In severe cases, retinoids, methotrexate, cyclosporine, infliximab, and hydroxyurea may be used.
+ Systemic corticosteroids are generally ineffective, and they can exacerbate the disease.
* Management of the ocular complications
o Ocular lubricants and punctal occlusion can be used to treat keratoconjunctivitis sicca.
o Trichiasis and cicatricial ectropion usually require surgical treatment.
o Topical corticosteroids are useful in treating the conjunctival, corneal, and anterior chamber inflammation. Nonsteroidal anti-inflammatory agents or oral corticosteroids are occasionally necessary.
o Whether systemic immunosuppression is effective for ocular disease is not clear.
o Corneal complications include the following:
+ Corneal melting, inflammation, and vascularization can be difficult to treat.
+ A bandage contact lens may retard the melting.
+ Topical corticosteroids can control the infiltration and delay the vascularization.
+ In some cases, progression can occur in spite of these treatments and can lead to the need for lamellar or penetrating keratoplasty.
Medication
Artificial tears and topical corticosteroids may be helpful.
Topical corticosteroids
Have anti-inflammatory properties and cause profound and varied metabolic effects. Modify the body’s immune response to diverse stimuli. Used to treat conjunctivitis, corneal infiltration, melting, or vascularization, and iritis.
Prednisolone acetate 1% (Pred Forte)
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Decreases inflammation by suppressing migration of polymorphonuclear leukocytes and reversing increased capillary permeability.
In cases of bacterial infections, concomitant use of anti-infective agents is mandatory; if signs and symptoms do not improve after 2 days, reevaluate patient. Dosing may be reduced, but advise patients not to discontinue therapy prematurely.
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